Professor Santiago Garcia Vallve

Academic Discipline: Molecular Biology, Bioinformatics, Chemoinformatics

Dr. Santi Garcia-Vallvé is an Associate Professor in the Department of Biochemistry and Biotechnology at the Universitat Rovira i Virgili (URV). He is a member of the Chemoinformatics and Nutrition Research Group. His research focuses on cheminformatics and computational drug design. He has contributed to the development of several virtual screening procedures aimed at discovering new antidiabetic compounds (such as partial agonists of PPARγ and dipeptidyl peptidase-4 inhibitors), anti-inflammatory agents targeting IKK2, protein tyrosine phosphatase 1B (PTP1B) inhibitors, and matrix metalloproteinase (MMP) inhibitors. Since the onset of the COVID-19 pandemic, his research has focused on the development of novel SARS-CoV-2 main protease (M-pro) inhibitors and the analysis of SARS-CoV-2 mutations. He is the co-author of more than 80 scientific articles and has been included in the Stanford list (2020–2024) of the world’s top 2% most influential researchers.