This is a state-of-the-art project that makes analysis protocols available to the scientific community and professionals using the most advanced infrastructures in the field of mass spectrometry. These are three state-of-the-art high-resolution mass spectrometers, which allow the detection, confirmation of organic compounds and the analysis of unknowns in different types of samples. Fields of application range from metabolomics to the environment and industry. The three technologies that the HRMS CATSUD-URV Platform incorporates are: GC-HRMS (Exactive GC is a high-resolution system consisting of a mass spectrometer and a gas chromatograph); UHPLC-HRMS (Orbitrap ID-X Mass Spectrometer ™ Tribrid ™ is an integrated mass spectrometer consisting of the combination of three mass analyzers (quadrupole, a double cell ion trap and the Orbitrap) with dual fragmentation techniques (CID and HCD), coupled to the Vanquish high-resolution liquid chromatograph Flex UHPLC, for very sensitive and ultra-high resolution MSn analysis); MALDI-HRMS (Exploris 120 Mass Spectrometer from Thermo Scientific with a Spectroglyph MALDI source, combines a high-resolution mass analyzer for accurate mass detection, coupled to a matrix-assisted laser desorption/ionization source (MALDI))

This is an innovative project that aims to provide the scientific community and professionals with advanced infrastructures for work and analysis at the nanometer or lower scale. The Platform uses two high-resolution electron microscopy equipment that are integrated into the Microscopy and Nanometric Techniques Area. The two technologies that make up the CATSUD-URV Nanotechnology Platform are: High-resolution scanning electron microscope (FESEM-FIB) and FETEM – Transmission Electron Microscope of atomic resolution.

Equipment of the archaeology laboratory for cleaning finds, restoration of ceramics, preservation of metals and glass, records of finds, drawing and photographic documentation of finds.

Supercomputer cluster equiped with programs to run theoretical chemistry calculations

Development, testing of biological effectiveness and registration (commercial use) of synthetic phytohormone derivatives (alone or in a mixture with fertilizers). We are equipped with the following mechanization: plot drill machine, combine harvesters, mechanization for fertilizing and spraying the plots, laboratory for seed and plants preparation. The cultivated area is 5 ha and we have experienced staff for verifying the biological activity of substances in field experiments on wheat, barley, corn, canola and other crops

The instrument allows performing reactions under microwave irradiation at temperatures and pressures up to 300 °C and 300 psi in either 10 mL or 35 mL sealed vessels at 0.2-7.0 mL and 2.0-25.0 mL scale, respectively.

The equipment is suitable for the transfer of technologies from laboratory scale to semi-pilot and pilot scale production, as well as for the large scale syntheses of up to 500 g of products. Equipment consists of duplicated glass reactor 10 L with accessories (anchor stirrer with speed control, thermometer (PT 100), cooler, distillation flask), extractor (liquid – liquid; glass; 20 L; propeller with speed control) and isolation filter for solid products (stainless steel with PTFE inert coating).

NMR spectrometer is dedicated to liquid samples measurement and can be equipped with 5mm Royal Probe with automatic tuning and matching or 3mm BBI probe. Auto sampler for 24 samples together with Royal Probe allows continuous measurement for 24/7 at room or elevated temperature.

High performance liquid chromatographer for analytical and semi-preparative purifications

NMR spectrometer can be used for measurement of liquid samples as well as for solid state NMR. For liquid samples is used 5mm HFX-Royal Probe, which allows to measure 19F NMR with 1H decoupling. The samples can be measured in temperature range from -100°C to + 140°C. For solid state NMR, 4mm VT HXMAS probe is used at room or elevated temperature.

Prusa 3D printer to make 3D prints out of PLA, PETG and ABS plastics out of models (e.g. molecules)

We have long and succesful experience with isolation and cultivation of several animal and human primary cell cultures such as neonatal rat cardiomyocytes, rat and human hepatocytes, human keratinocytes, human umbilical cord endothelial cells, human dermal and gingival fibroblasts

Used to study the chemical composition of all kinds of samples (gas, liquid, solid), such as natural products, organic and inorganic pigments, or minerals – suitable for qualitative and quantitative analyses in both far- and mid-infrared regions

Used to identify the chemical composition of the solid or liquid samples, e.g. waxes, gels, pastes, filaments, pieces of wood and other natural samples, minerals, and metal pieces, etc. – suitable for qualitative and quantitative analyses

This phantom allows testing of X-ray based imaging techniques (including CT).

Ultrasound machine suitable for whole-body imaging

The Necropsy room is equipped with a big necroscopic table (cm 248×129) provided with an elevator system and four small necroscopic tables (cm 130×50). All tables comply with biosafety and biosecurity standard. A refrigerated room (+2°C) cm 281x108x235 and a freezing room (- 20°C) cm 281x108x235 allow storage of large amount of material. The room is equipped with four sinks for washing and disinfection of tools utilized for necropsy activities and an aluminum cabinet allows their preservation. All the procedures are carried out in compliance with the biosafety and biosecurity rules. A laboratory hood allows the storage and processing in complete biosafety of the tissues taken during the necropsy for the execution of collateral examinations (histological, bacteriological, toxicological examination).

The Center for Instrumental Analysis is the is the shared instrument facility for chemical analysis at the Department of Pharmacy. It includes 3 high-field NMR spectrometers (700 MHz, liquid 1H/13C/15N 5 mm cryo-probe or CP-MAS probe; 600 MHz, 1H/13C/15N/31P 5 mm cryo-probe, SampleJet autosampler; 400 MHz, 1H/BB 5 mm inverse probe), one Linear Trap LC-MS system, one Triple Quadrupole LC-MS system, one Single Quadrupole GC-MS system. Purchase of a high-resolution Orbitrap instrument is planned.

Share Journals is the platform for the management and publication of open access scientific journals on behalf of the SHARE Interuniversity Consortium. Share Journals has been created by the University of Naples “Federico II “- Centre for Libraries. Since 2015 hosts the research publications of the Universities participating in the SHARE alliance, which involves the collaboration of 11 Universities of Southern Italy. Research publications are submitted to a double – blind peer – review process and are published in Italian and in English.

The IT platform is employed to publish and disseminate e-book series in Open Access. Share Books has been created by the University of Naples “Federico II “- Centre for Libraries. Since 2015 hosts the research publications of the Universities participating in the SHARE alliance, which involves the collaboration of 11 Universities of Southern Italy. Research publications are submitted to a double – blind peer – review process and are published in Italian and in English. The University of Naples Federico II owns a digital publishing brand, FedOA Press.